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YIL 781
CAS No. 875258-85-8
YIL 781 ( —— )
产品货号. M33951 CAS No. 875258-85-8
YIL781 是有效的、具有口服活性的胃促生长素受体(GHSR) 的拮抗剂。YIL781 可改善大鼠体内葡萄糖稳态。YIL781 可抑制饥饿素诱导的钙反应，pIC50 值分别为 7.90 和 8.27。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥568 | 有现货 |
|
| 5MG | ￥783 | 有现货 |
|
| 10MG | ￥1252 | 有现货 |
|
| 25MG | ￥2565 | 有现货 |
|
| 50MG | ￥3855 | 有现货 |
|
| 100MG | ￥5271 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称YIL 781
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述YIL781 是有效的、具有口服活性的胃促生长素受体(GHSR) 的拮抗剂。YIL781 可改善大鼠体内葡萄糖稳态。YIL781 可抑制饥饿素诱导的钙反应，pIC50 值分别为 7.90 和 8.27。
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产品描述YIL781 is a potent and orally active ghrelin receptor (GHSR) antagonist. YIL781 produces a greater improvement in glucose homeostasis in rats. YIL781 inhibits the calcium response induced by ghrelin with pIC50 values of 7.90 and 8.27, respectively.
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体外实验——
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体内实验——
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同义词——
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通路GPCR/G Protein
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靶点GHSR
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受体GHSR
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研究领域——
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适应症——
化学信息
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CAS Number875258-85-8
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分子量409.5
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分子式C24H28FN3O2
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO 中的溶解度 : 100 mg/mL (244.20 mM; 超声助溶 )
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SMILESO=C1C=2C(N=C(C)N1C[C@@H]3CN(C(C)C)CCC3)=CC=C(OC4=CC=C(F)C=C4)C2
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. William P Esler, et al. Small-molecule ghrelin receptor antagonists improve glucose tolerance, suppress appetite, and promote weight loss Endocrinology. 2007 Nov;148(11):5175-85.?
产品手册
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YIL 781
YIL781 是有效的、具有口服活性的胃促生长素受体(GHSR) 的拮抗剂。YIL781 可改善大鼠体内葡萄糖稳态。YIL781 可抑制饥饿素诱导的钙反应，pIC50 值分别为 7.90 和 8.27。
